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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da851dfdcd08c8fa78a9dc1653779d6543fe340aaf0a320ce8a1e281228ab7d0' 
  AND token = 'B5CjA0IDqk+MuyJmOlrPaDz600uafRJvx+jNb/OkMbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}