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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e51c2e8a3e63457639c060841231a1d50506a9f50431c3b14da9c527af419f5' 
  AND token = 'PEtKIf9TArSMfxoTLMuASgxWFp6L9MkaTku5w93H/uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}