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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c9b8ad5bc691ad0d44abff5f76a3472abd2fc69018f900dc1c1cf851bf5384' 
  AND token = 'A3/8lKMp0xSv3s0yMmz1RkJidvDwh2dI1ejVNcaDWe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}