SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4b145781fe62f42ac26874989e6de0b41ae1bc84bd4befc72ad16a569e1571' 
  AND token = '4Sn8b1eV7anXo5U4KRjvV6pfsiQji9Oo8wd28YoAtwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}