SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00b3fc40cdabdbc85391da517cb906ffa17d1926cf8c2911d24a728950f93d8' 
  AND token = 'ZrNy3l+3xg+FkWw6hp04s6TwxEp88vDOWQv91yedLg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}