SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7abc44baf55c4bcd68e0941cd1bcf5eb611133817f79282264f6b43dceb7b101' 
  AND token = 'Vt0a7YiNPMR8uUL2CmLM9B0jHZUF5LbIdMPJAYnH3+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}