SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4b2d034122a651a09c171c56805c242be3e0fd5dc3e478398718e56e527b8d' 
  AND token = 'nNcT0nOLInhcy8AT7T/Wr/CRn8aWa1F6oFsnugtShT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}