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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4244e9be062c9d9df1983196ee258f7667c334d78094cb86df91cb3da0da56' 
  AND token = 'HhNLb5u2qOODe2Y6SRLaXp0ISM39XelHUBUpclP8xwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}