SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8391fd2e0c139b3b221d988b3edf7d697e67f723e16467bf862265be3e9608ed' 
  AND token = 'aPa/95rNBg1sKBtiMBUnDtDDgNRtkwDYmfDARugyslM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}