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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d37349088d514f1ae8f551bb207b09969737323d2473346021bed6e221b2442' 
  AND token = '6plGkvLFos4vWcmFu4kLxR6hO1s08SXVIXO+NlDa0/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}