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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606c47dd98ec2a8a341fb888b77aa3c86a829254e760c8cb416f6d020db6ecdf' 
  AND token = 'xuo2BRsdWCUIT7ucGtVd29mnDMXWtrqk52k5EH7FhiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}