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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f728b05b03a7a665dd73edbd3da8cea73f2744f64b7fb327dd82619fcd7c0242' 
  AND token = '737FSh0/FjgLzDiur83HopcDUEbHxnqs5qEKJ5T+cLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}