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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ae574c916de079572455dfb97c25a3fd882f7cf5032c3a5ade4de5cd4561e5' 
  AND token = 'Ge1ufa3pWeTsQz84DoFcQctwhlT3QwWigk1iJKcr3kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}