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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3cc0654bebf869daa46ea5c6b283637abf388b9ed4f2a997e82cb2fb39738be' 
  AND token = 'vqZcSNCDDeONWlPRBrFNK9MGGoEB+NIWkapRcYXXTPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}