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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a8df18b08961c2396b9395bb777d827e9d067d839bb5628e8736cfcb1d1c44' 
  AND token = '7eIpZiJ7fPnhJcToIPrJtCwSMvev8IM7p7oRK38GLlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}