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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff1fdd6159045e0ab7f4e9a17b9858c457fe0b9ffaddbbb13255c1c538ef3d0' 
  AND token = '5yO9rhd1l3ki0OycvcTRWKDF/X5Fn6U2gDmDN41Y4P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}