SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ea1a436f5d966df3bb7cf121b5b6c6f7d3f6f042358009d426eea82bc1f28a' 
  AND token = 'TW422fNfIb0iSHiHw0mkt0NoMuNk8ralL9Gqof4SDsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}