SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c110b27594033b9acc146c7e648f396aa66e7667dfda6206b46b6885297b681f' 
  AND token = 'IijzqSkaMRIPYNOgpI1b8tbHhcyH2vJHWpBK46w9kxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}