SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53bc0c700569509288811eaea1412318534d5a53e03ac648554c6307bc7d572' 
  AND token = '45EL/V2uKsjuAccCSYkhgxLPLBEhE/WT4JiLOA5ogt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}