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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64c049a94b2d12da969e95dc821c8f65218430caaaf526a1dc9a2b93ffdbeb5' 
  AND token = 'AZkelvxfrdj2wcF5UUwf6nIepr5umFggMcpNik2JjpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}