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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed2de6ec7084147c11061c98bb80242890731e054649fd61a5d953c06ad0d81' 
  AND token = '26neh/uJKaZjto8Cgze6PRRRA2FxWTnz4qIy4VI9EbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}