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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293a2c4bdb4c20fbf757b1d615c917b8c6f1a977433a2259a1076382c97d66d0' 
  AND token = 'BFO2vT6ZVy8qVfdmcGEbAL81xOeqhuXSk4ciB5ng5Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}