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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07a2f466b102d1ddd89ede13737f3677e8f0858419fb3d13e4efb13cdffb50cb' 
  AND token = 'IAcSIR9VPJCicr/rUOIsAdGV7+N3Pf6BFQaxdzVn+Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}