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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcbc3874e23575ed842e66ae5d5b129aada204ddc6e0318129bf753c518bd52e' 
  AND token = 'vjUaGTzP0TbSpImInKZ7S5hY1poa5HJrzgZdbDuk0SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}