SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f821939eb0e1522dbc80ead6ad2caeb00c2613ba9ef4b9925a969d21d64c06fe' 
  AND token = '/47UwOkIMWmXGWFY7AeZssP0CYJdP4uQdfrQlcwu11Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}