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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed05b3b4583897dd412fe3c4da2f1f65cbf8bc12a73ea65b8e64f5639a2314b' 
  AND token = 'uXMdEk7D6/Rs79y+zVj6479GnhPwhijbK73qXbEx0oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}