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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e99f801974bfed63bd1855f7723cc1593dea1dd30cabe94a9060dcbb26861c1' 
  AND token = '3NAT7w5tUNAUr6W8T7HVyynbDk6P6M8YEl/G+AeY3/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}