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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac150a00ef1550b8c4df2239c6638c12ef3eb8fda4bb56cd358967715c73616a' 
  AND token = 'sGbj2RsM6yuF2E4kaHyWIpt5OvEoB4SAFz2o6YFEDtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}