SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34327ec3543f85c187d2a437e09b87e8077f3c41ad15ca4a70df9212ce451f24' 
  AND token = 'z91n8hxYXcpviTfYsPrju3RGWbpvbRkuq3AgZ3N/vUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}