SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c3d7a35194ffd4890279acd24d2feda84f2bf7b4cd9cb0daf42d1ba471dd21' 
  AND token = 'Z0hLYMtpvRjbWs2AobeMu7b+4iKOQYvpAeIa8hFrutY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}