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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce90004130b7ea6a7c856f2f310063046f4ce07b4b0bb1952bf8a39788c9a34e' 
  AND token = 'EfkENIANz7/mKsJi3cigGBEkplDID330amIK9uIKxEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}