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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd000ad4bb9ded41148c7b642a2bf094796a5885020932ef85f9be766f8a18e13' 
  AND token = 'TG4HSwSXT+L8nJiwpYiBj4AvRaYUMQkjS3X8igg9yws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}