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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '414990faf4e2c86d1cf42ab14b4eebceb8283431a41e13ff7e33829c18eec7be' 
  AND token = 'rGRE7lq3NqKfb4zJ7hehU+4aeRGuxlwEUYAOLdfQJIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}