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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d90e78506d1f596bc764127e1a2d43b5df28bdca23eae754c498bade1a03bcd' 
  AND token = 'zpNIk7RIRvAMAsgGIlEtUjjPgNZ2FXcwkyCgHrJ+yjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}