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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4505bb200a5774f00e7063f84aefcf32dc1707120765e1fc718eba633816e7d' 
  AND token = 'LBUF1u7R3hIBR4DqBOrIN/cwS3BrS9pD9vsPWoZmaPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}