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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187f67ee6a89047dc722c250d2a55d09bb68fdcc1b57b5e042f559bf5d691de4' 
  AND token = 'Xp7Nw0R/ECEuXMBwZtb1zrwCw0jx94ofEinTxmLkvag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}