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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4294fcc6eab7143f5bc5976efe62305428da6d9dfc0c1c69bfc13b3dc61cc04' 
  AND token = 'usCO5do/a23hFl/tcU/SS4567pha4+FNfXhLmctuo18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}