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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c757c82663df03f424bb0be2d973ad3bd752f5598f4d5d2658f6cc349ee7386e' 
  AND token = 'YGprr+87SoVRQoc+qfexnnoAFH9JKNpDUZoOvh2AoN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}