SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e14167b5501c00011b9d0a002e7fe1a19e9c222e798881ad94b88823d4078f2' 
  AND token = '08izVJGS655Nsx6NgO/qVY+e6Vy/RRmfIFwaWfckflk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}