SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665735b5ab3b59a7328d644c47042a92cbe59a4c76667c6e4a75cab28da8646a' 
  AND token = 'JbnWikeX/XpjxNYI3nnPcbtGclT2QqcmjO2WL8iJ7Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}