SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8743b24f3d99cec8f4a445c855068cd52c9efa1cd5631272e8cfefdef47e74c' 
  AND token = 'O95VEBASW9mHG+UkH4a20oN1xujuVgdwc0D6PTjOixk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}