SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5c79629c2afe94cea06d7638eb3ae939da25dc137d931c31b8c548f7eed41e6' 
  AND token = 'j4Q4pxPI/EzMj1jo7SUKcRQvl5U99U5RUUztIRgl6Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}