SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee26df1dd8d759f68e0e1fe580dec791e34d7cd2fec57d8350bfe3c6ed1a920' 
  AND token = 'y5KENIGTcNHyKMa00PDucUxrBAMp8pQ3hsoiKcRJMuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}