SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e41a05e8024cc3aa47884308b7750f1fae4665e520fd9bbed8d29ba4705c54' 
  AND token = 'nTextIauR05FoTOMpn69lBkDglM2f23CQO34UdtLMfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}