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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06bdfa307063ead1c9becc989eb728b6800dcd82aafbd88c9834546b44e86f08' 
  AND token = 's+JmcrZ28Fmm6q/antGO0fasYg7Pe6MOC0KW8hTwn6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}