SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af9be27a8ab2a373b825f164f0ab8ec3bdf4b81a011b9a4f3ef40204368c10cc' 
  AND token = 'kyS01B3uE5PG/+2AxRZ615ch123qCIVWjk9LECRTOGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}