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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fcb155b78d1e6955c85d2a20c8b8ef611dda5a5be0f04087c126fc426ed7318' 
  AND token = 'VZ/MpDZuWsOwCDvj4k8NWC2i7kwGhjTPSVU1eH8lwWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}