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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c49c9ce1fb4baeca5c057e62d1104e3bef0d9f80cbced725aceeb9da124c86' 
  AND token = 'LVZUjmJqaCG5B8ytIaa8P45m1j8NbPIT1nNITbgKG90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}