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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5beef2c1251a7b2c4814f0eef6de7129ea668d4868d6a52453e72b679696c7d' 
  AND token = 'Z5DzT3PqD0WSo0JCeG0VSNoJ1JCyzzPF7uKCvpyvXE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}