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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cec0cf9396fe6e5cd46c73c66996ee8c4163580e072747b45f7dc80f7fc0a0' 
  AND token = 'jH4wFL0xpYANRgTCoUle02WkXF0F6GikALr44LnovMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}